Cholera and LT-ETEC (enterotoxigenic Escherichia coli) are both major causes of traveler’s diarrhea, especially in areas with poor sanitation. Both diseases can cause severe dehydration and even death if untreated. Fortunately, Dukoral, an oral vaccine, offers protection against these two conditions.
What is Dukoral?
Dukoral is an oral vaccine that protects against cholera caused by Vibrio cholerae and LT-ETEC diarrhea caused by enterotoxigenic E. coli. The vaccine contains inactivated Vibrio cholerae bacteria and cholera toxin B subunit, which stimulate the immune system to build resistance against both cholera and the harmful toxins of LT-ETEC.
How is Dukoral Administered?
Dukoral is easy to take with two doses for adults and three doses for children between 2-6 years of age:
The first dose, followed by a second dose 1–6 weeks later (children 2-6 get a third dose 1-6 weeks after that).
It should be taken in the buffer solution (provided) to neutralize stomach acid, helping the vaccine reach the intestines effectively.
For full protection, it’s recommended to complete the vaccination series at least one week before travel to cholera-endemic areas or regions where LT-ETEC is common.
Who Should Get Dukoral?
Dukoral is recommended for individuals at risk of cholera and LT-ETEC, including:
Travelers to cholera-endemic regions, especially in South Asia, Africa, and Latin America.
Humanitarian aid workers or anyone working in areas with poor sanitation.
Residents of endemic regions.
Check with a healthcare provider such as us to determine if Dukoral is the right vaccine for your health needs.
Efficacy and Duration of Protection
Dukoral provides 85% protection against cholera and approximately 60% protection against LT-ETEC diarrhea in the first six months. Its effects typically last for up to 3 months for LT-ETEC and up to 2 years for cholera, after which a booster dose is recommended for extended travel or continued risk. Keep in mind, Dukoral should not replace standard preventative hygiene measures.
Safety and Side Effects
Dukoral is generally safe, with mild side effects such as nausea or temporary abdominal discomfort. Severe reactions are rare, but always consult your healthcare provider if you have concerns or allergies.
Conclusion
Dukoral is a valuable tool for protecting against both cholera and LT-ETEC diarrhea, common concerns for travelers in areas with inadequate sanitation. By taking Dukoral, you’re reducing your risk of these preventable diseases. If you’re planning to travel consult a travel clinic such as ours to discuss vaccination options and ensure you're well-protected.
Stay healthy and safe with Dukoral, the oral vaccine for cholera and LT-ETEC diarrhea!
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For information on another vaccine currently available for cholera in the Canadian market, please consult the link below:
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